S.E.M.I. Side Effects May Include... PC

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Platform:

PC: Windows

Release date:

Jan 23, 2026

Developers:

Two Horn Unicorn

Publishers:

Two Horn Unicorn

Genres:

Action, Beat'em up, Platform, Puzzles, Roguelike, Third Person

Themes:

Comedy, Indie, Martial arts, Monsters, Physics, Psychological, Surreal

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S.E.M.I. is a single-player and co-op action platformer with puzzle elements. Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects!

translateLanguage

Interface:

English, French, German, Japanese, Korean, Portuguese, Portuguese - brazil, Russian, Simplified chinese, Spanish, Spanish - Spain

sports_esportsController

Mouse and keyboard

Gamepad

peopleModes

Single Player

Cooperative

Online

Yes

storageRequirements

Minimum

Windows 10

CPU

Intel Core i5 series or Ryzen series

Memory

8 GB RAM

Gpu

GTX 960 or AMD R9 290

DirectX

Version 11

Storage

3 GB available space

Recommended

Windows 11

CPU

Intel Core i7 series or Ryzen series

Memory

8 GB RAM

Gpu

GTX 1660 or RX6600

DirectX

Version 12

Storage

3 GB available space

albumFormat

Digital

attach_moneyPayment

Paid DLCs

storeStore

Steam link

Jan 23, 2026

“S.E.M.I. Side Effects May Include...” is a third-person action game featuring martial arts, comedy and indie elements, developed by Two Horn Unicorn for PC and released in 2026. The game offers single-player gameplay and features cooperative play. Available on Steam.

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